High Scalability Building bigger, faster, more reliable websites.

Hello,everybody,I'm plant to building a new website like 2008.sina.com.cn 2008.sohu.com .site contents have pic news,text news,and video news.user blog ....now I have a question to ask everybody,I hope can get usefully information to here.
status:
100,000,000 people /per day
50,000 people /peak time
more than 200 servers

OpenBSD/Opensuse
Apache Fast CGI modules
lighttpd for picture
Mysql
varnish
LVS
lucene search

do you have a good idea to it?thans for everybody!